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To your good health

Anything under 8,000 IU of vitamin D won't cause an overdose

DEAR DR. ROACH: Several years ago, in my early 80s, my gynecologist told me (like all women who mainly stayed indoors) that I should be taking 4,000 IU of vitamin D3 daily. Yet today, I read an article warning that many people are overdosing on vitamin D. Is this really a concern? — L.M.

ANSWER: Overdosing on vitamin D is dangerous. Last month, I had a patient who had elevated levels of calcium, which caused typical symptoms of confusion, vomiting and muscle weakness. She was found to have a very high blood vitamin D level. (She had mistaken the instructions for taking vitamin D.)

I have also seen vitamin D toxicity in people who are prescribed 50,000 units once a week for a month and mistakenly take this each day. (I don’t prescribe this formulation as I have seen mistakes like this too often.) Toxicity is almost unheard of at 4,000 units daily. Up to 5,000 or even 8,000 units of vitamin D3 daily are very unlikely to cause excess.

Screening and treatment for vitamin D deficiency is less often done since the publication of a large study that showed few benefits to treatment. However, it is still appropriate to consider vitamin D deficiency in some high-risk groups.

This includes older adults who don’t go outside much but also people who don’t absorb calcium well (especially those with a history of bariatric surgery, inflammatory bowel disease, or celiac disease). It can also occur in dark-skinned people or those who wear sun-protective clothing all the time.

Some medicines (especially for epilepsy) can increase the body’s metabolism of vitamin D. I recommend obtaining your blood levels prior to starting vitamin D supplementation to confirm that the level is optimal during therapy.

DEAR DR. ROACH: Individuals who have an endoscopy or a colonoscopy are sedated before the procedure. When they awake, they are usually fine. I recently had my second cystoscopy, and like the others, it involves inserting a scope to check out, in this case, my bladder.

The only sedation is an injection of Novocain into the penis. Then I had to wait about 10 minutes, and in came the scope. It is the most incredibly uncomfortable procedure that I can remember undergoing. It lasts for about 5 minutes. Is this why you don’t get sedated for this procedure? — E.B.

ANSWER: I get frustrated when I hear about patients not getting adequate pain relief for a procedure. Women who get IUDs or an endometrial biopsy often have inadequate pain relief, and men getting prostate biopsies are not offered anesthesia often.

While many people tolerate them without much discomfort, I have heard from many men and women who say that these procedures are the most pain they have ever had in their lives. How we are affected by medical procedures varies dramatically from one person to another. Many people want to appear stoic, but this is not necessary, helpful or good for you.

For cystoscopies in particular, I would say that 10 minutes may not be enough time for the local anesthetic to work; 15-20 minutes is usually recommended. Simply allowing the patient to watch the procedure has been shown to reduce pain and anxiety.

The medical literature provides other options, including nitrous oxide (like some dentists use), a nerve block (anesthesiologists usually do this), or a different local anesthetic. If you need another cystoscopy, please feel empowered to ask for better pain relief when you are next recommended for it by your urologist.

Dr. Roach regrets that he is unable to answer individual letters, but will incorporate them in the column whenever possible. Readers may email questions to ToYourGoodHealth@med.cornell.edu. (c) 2025 North America Syndicate Inc. All Rights Reserved

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