Dear Annie: My sister and I have not spoken in three years following a falling-out over our mother's estate. I won't rehash the details — suffice it to say, neither of us came out looking entirely clean. We were never close growing up, but we were friendly enough as adults, and I miss ...

DEAR DR. ROACH: I am a 70-year-old female in fairly good health with a number of diseases/conditions that are fairly well-controlled. I take about 15 prescription and over-the-counter meds a day (including methotrexate) for my Sjogren's symptoms and other conditions, plus a statin. Nine ...

Dear Annie: My dearest friend and I go back over 50 years. We've seen each other through everything, high and lows. Recently I became disabled and can no longer drive. I'm also a widow. I'm not asking anyone to chauffeur me around (I have that handled), but a phone call here and there ...

DEAR DR. ROACH: I have been taking 25 mg of amitriptyline for sleep for several years; I am 79 and have noticed occasional difficulty remembering some facts. I read that this drug can affect cognition. I don’t believe that amitriptyline is really effective in helping me sleep, so I have ...

Dear Annie: My sister and I have always been close. We grew up sharing clothes, secrets and late-night phone calls, and for years I considered her my best friend. But lately, every conversation with her feels less like a conversation and more like a contest I never signed up to enter. If I ...

DEAR DR. ROACH: Any thoughts on milk thistle supplements in fatty liver disease that was diagnosed by an ultrasound due to elevated AST and ALT levels? — B.S. ANSWER: Milk thistle (sylmarin) has had mixed results in clinical trials regarding metabolic-associated steatotic liver disease ...